RecruitingNot ApplicableNCT05379673

The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

Recovery of Ventilation After General Anesthesia for Robotic-Assisted Laparoscopic Nephrectomy or Prostatectomy: The Effect of Oxygen Supplementation


Sponsor

Stanford University

Enrollment

60 participants

Start Date

Oct 4, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria3

  • American Society of Anesthesiologists (ASA) physical status I-III
  • Body mass index (BMI) less than 40 kg/m2
  • Scheduled to undergo robotic-assisted radical laparoscopic nephrectomy or prostatectomy.

Exclusion Criteria3

  • Patients with a diagnosis of chronic obstructive pulmonary disorder (COPD), severe neurological, cardiopulmonary, psychiatric, or untreated thyroid disorder
  • Chronic pain condition that is being treated with opioids
  • Patients with a hematocrit lower than 30% at the end of surgery, or those with an excessive blood loss, requiring transfusion of blood products during surgery.

Interventions

OTHEROxygen Gas for Inhalation

Oxyhemoglobin saturation (SpO2) higher than 96% vs SpO2 between 90% and 94%.


Locations(1)

Stanford University School of Medicine

Stanford, California, United States

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NCT05379673