Effect of Esophageal Contractile Reserve on Changes in Esophageal Motility and Symptoms After ARS in Patients With GERD
Effect of Esophageal Contractile Reserve on Changes in Esophageal Motility and Symptoms After Anti-reflux Surgery in Patients With Gastroesophageal Reflux Disease
Shandong University
70 participants
Apr 22, 2022
OBSERVATIONAL
Conditions
Summary
rapid swallow (MRS) can assess the contractile reserve capacity of the oesophageal body and identify and diagnose oesophageal motility disorders, but the impact of preoperative oesophageal reserve capacity on postoperative symptoms and motility in patients with GERD remains unclear. The aim of this study was to assess the effect of pre-operative oesophageal reserve capacity on post-reflux symptoms and motility in patients with GERD by using a high-resolution oesophageal manometry-based provocation test, MRS, to track pre-operative ineffective oesophageal motility (IEM).
Eligibility
Inclusion Criteria4
- Age over 18 years old
- Patients to be treated surgically for gastroesophageal reflux disease
- Ineffective esophageal motility diagnosed by high resolution esophageal manometry according to Chicago Classification version 4.0
- Obtaining Informed Consent
Exclusion Criteria3
- Previous other upper gastrointestinal surgery
- Pregnant women and other people with contraindications to surgery and tests
- Other specifically defined esophageal motility disorders, such as nutcracker esophagus
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Interventions
Regular follow-up visits to record information about the patient's surgery and routine post-operative examinations
Locations(1)
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NCT05380791