RecruitingNCT05386043

Registering Genomics and Imaging of Tumors (ReGIT)


Sponsor

Indiana University

Enrollment

20 participants

Start Date

Jul 18, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This study is investigating how brain tumors might mutate over time, and whether new brain imaging tools like MRI and PET can predict these mutations.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is building a research database by collecting genetic information and MRI imaging data from people with brain tumors called gliomas (grades II through IV). By analyzing DNA patterns alongside imaging and health records, researchers aim to better predict outcomes and develop more personalized treatment strategies for brain cancer. **You may be eligible if...** - You are between 18 and 89 years old - You have been diagnosed with or are suspected to have a glioma (a type of brain tumor, grades II–IV) based on imaging or physician review - You are willing to have brain MRI scans and tissue samples collected as part of your standard care **You may NOT be eligible if...** - You are unable to have an MRI (for example, due to a pacemaker, metal implants in the body, or severe claustrophobia) - You have serious unstable medical conditions that would make participation unsafe - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGFET F-18

PET scan with FET prior to biopsy

DRUGO-15 Radioisotope

PET scan with O-15 Water prior to biopsy

PROCEDURECT scan

CT scan prior to biopsy

PROCEDUREMRI with gadolinium-based contrast

MRI prior to biopsy

PROCEDUREBiopsy Collection

Biopsy collection during standard of care neurosurgery for glioma diagnosis/excision


Locations(1)

Indiana University School of Medicine

Indianapolis, Indiana, United States

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NCT05386043


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