RecruitingPhase 1NCT05391490

Allogeneic T Cells Expressing T Cell Receptor-KDEL and the Chimeric Antigen Receptor CAT19 for the Treatment of Advanced CD19+ Malignancies


Sponsor

University College, London

Enrollment

12 participants

Start Date

Feb 6, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

KCAT19 is a single-centre, non-randomised, open-label Phase I clinical trial of an Advanced Therapy Investigational Medicinal Product (ATIMP) in adults (age 16-65 years) with high risk, relapsed/refractory (r/r) B cell malignancies.


Eligibility

Min Age: 16 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying KCAT19 T cells for people with blood cancer. The study is currently recruiting participants at 1 location. People eligible for this study include aged 16 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

GENETICKCAT19 T cells

Allogeneic, cord unit derived KCAT19 T cells


Locations(1)

University College London Hospital

London, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT05391490


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