RecruitingNot ApplicableNCT05395715

Conditioning Electrical Stimulation to Improve Outcomes in Cubital Tunnel Syndrome

Conditioning Electrical Stimulation Enhances Recovery Following Surgery for Severe Cubital Tunnel Syndrome: A Double-Blind Randomized Controlled Trial


Sponsor

University of Alberta

Enrollment

30 participants

Start Date

Apr 1, 2022

Study Type

INTERVENTIONAL

Summary

Cubital tunnel syndrome is the second most common compression neuropathy. In severe cases, functional recovery, even with surgery, is often poor. Therefore, alternative adjunct treatments capable of increasing the speed of nerve regeneration are much needed.


Eligibility

Min Age: 18 YearsMax Age: 79 Years

Inclusion Criteria4

  • Patients aged >18 yr,
  • If signs and symptoms of severe CuTS (ie, McGowan-Goldberg grade 3) were observed,
  • If needle EMG examination showed evidence of chronic motor axonal loss and reduced recruitment in the ulnar-innervated intrinsic hand muscles, and
  • If electrophysiologic evidence of severe motor axonal loss with motor unit number estimation (MUNE) greater than 2 standard deviations below the normative mean.

Exclusion Criteria1

  • \) Patients were excluded if they had concurrent nerve injury, prior surgery for CuTS or coexisting neurologic conditions

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Interventions

PROCEDUREElectrical stimulation

Patients with cubital tunnel syndrome will receive either surgery and sham stimulation, or conditioning electrical stimulation 7 days prior to surgery


Locations(1)

University of Alberta

Edmonton, Alberta, Canada

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NCT05395715