RecruitingNCT05400707

Triage - Symptoms and Other Predictors in an All-comer Emergency Department Population

Triage - Symptoms and Other Predictors in an All-comer Emergency Department Population (EMERGE V-VII)


Sponsor

University Hospital, Basel, Switzerland

Enrollment

6,467 participants

Start Date

May 17, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This study is to evaluate a tool capable of improved risk prediction regarding the 30-day mortality. The primary objective of this study is hospitalization, ICU-admission, morbidity and mortality in correlation with external validation of International Early Warning Score (IEWS) and decision-making processes regarding diagnosis, treatment and disposition in the ED.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Patients presenting to the ED of the University Hospital Basel over a timecourse of 9 weeks in 2022, 2024, 2026

Exclusion Criteria3

  • Obstetric, ophthalmologic, and paediatric patients will not be included
  • unwillingness to participate
  • insufficient ability to communicate with the study personnel.

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Interventions

DIAGNOSTIC_TESTAssessment of vital signs

heart rate, blood pressure, body temperature, respiration rate, peripheral capillary haemoglobin oxygen saturation)

DIAGNOSTIC_TESTAssessment of patient mobility at presentation

Patients are asked how they assess their own mobility: - Stable walking without aids or limited mobility with aids (walking aid, wheelchair, lying down).

DIAGNOSTIC_TESTAssessment of level of consciousness by AVPUC scale

Assessment of level of consciousness by AVPUC scale (alert, new confusion, verbal, pain, unresponsive, new confusion)

DIAGNOSTIC_TESTAssessment of symptoms patients presenting when admitted to ED

Questionnaire with a predefined list of 37 symptoms

DIAGNOSTIC_TESTAssessment of what matters most in patients of 65 years and older

Patients over the age of 65 are asked the following: "generally asked: what matters most to you at the moment?" and "why is that important for you?".

DIAGNOSTIC_TESTAssessment of Decision-making in senior physicians

Questionnaire consisting of 10 questions about the decision-making processes in the emergency department and the factors that form the basis of their decisions regarding the diagnosis, treatment, and disposition of the patient.

DIAGNOSTIC_TESTPain Numeric Rating Scale (NRS)

The NRS is a segmented numeric version of the visual analog scale (VAS) in which a respondent selects a whole number (0-10 integers) that best reflects the intensity of his/her pain ('0' representing one pain extreme (e.g. "no pain") to '10' representing the other pain extreme (e.g. "pain as bad as you can imagine"))

DIAGNOSTIC_TESTClinical Frailty Scale (CFS)

The CFS is a commonly used score to assess frailty. It was developed within the Canadian Study of Health and Aging and consists of a 9-level ordinal scale ranging from very fit (score 1) to living with very severe frailty (score 8), and score 9 reserved for those who are terminally ill.

DIAGNOSTIC_TESTPeripheral Perfusion Index (PPI)

The PPI is derived from the photoplethysmography signal of pulse oximetry and represents the ratio between the pulsatile component (arterial compartment) and the non-pulsatile component (non-arterial tissues) of the light detected by the sensor. PPI can provide information for resuscitation in shock, outcome prediction in critically ill patients and may serve as an adjunct triage tool.

DIAGNOSTIC_TESTCapillary Refill Time (CRT)

CRT provides a standardized assessment of capillary flow dynamics and is most assessed at the fingertip in clinical practice. A prolonged CRT in patients with septic, traumatic and cardiogenic shock has been associated with increased mortality and might be used as a resuscitation target in patients with septic shock.

DIAGNOSTIC_TESTMottling Score (MS)

Mattling is a characteristic discoloration of the skin resulting from reduced skin blood flow and has been shown to be associated with tissue hypoperfusion. The MS provides a simple scale (0-5) to characterize the extent of skin mottling around the knee and the severity of mottling is associated with adverse outcomes.

DIAGNOSTIC_TESTMental health complaints

Mental health complaints require safe, efficient risk stratification to distinguish primary psychiatric conditions from medical causes or comorbidities. Because current medical screening practices are inconsistent and unvalidated, this study will use prospective routine ED data to evaluate triage assessments of psychiatric likelihood and identify opportunities for standardized, evidence-based screening.

DIAGNOSTIC_TESTAltered mental status - a vital sign

Delirium is a common and high-risk condition in older ED patients, and early detection is crucial to improve short- and long-term outcomes. This study will use routinely collected ED screening data (modified Confusion Assessment Method for the Emergency Department (mCAM-ED) and the four-item Abbreviated Mental Test (AMT-4)) to describe delirium prevalence and evaluate delirium identification in the emergency setting.


Locations(1)

Department of Emergency Medicine, University Hospital Basel

Basel, Switzerland

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NCT05400707