RecruitingNCT05403177

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

Sponsor

University Health Network, Toronto

Enrollment

500 participants

Start Date

Jun 23, 2022

Study Type

OBSERVATIONAL

Conditions

Breast Cancer

Summary

The Marathon of Hope Cancer Centres Network (MOHCCN) is a national network of cancer centres that pursue collaborative cancer research in precision medicine (an emerging approach for disease treatment and prevention that considers individual variability in DNA, environment and lifestyle) to accelerate the discovery of innovations and improve the health outcomes for cancer patients

Eligibility

Min Age: 18 Years

Inclusion Criteria6

Patients with histological and/or cytological confirmation of blood or solid tumor malignancies. For tumour types where pre-surgical biopsy is not routinely performed to confirm a pathologic diagnosis of cancer, patients may consent to this protocol, but eligibility must be confirmed after pathology is finalized demonstrating presence of malignancy
All patients must be able to satisfy the required minimum data elements for the 15k gold standard cohort through:
Already existing data that satisfies the minimal requirements of a gold standard case (refer to Table 1)
Have sufficient biospecimens (tumor and/or blood samples) available for more comprehensive molecular and immunophenotypic characterization
Patients who do not satisfy the required minimum data elements but would like to participate, maybe requested to donate blood and undergo a fresh biopsy if the archived Formalin-fixed paraffin-embedded (FFPE) samples are not available, or in cases where a fresh tumor biopsy is deemed necessary for molecular profiling.
Participating patients must agree to share their anonymized clinical and genomic data