AZA + Venetoclax as Maintenance Therapy in Younger Adults With AML in First Remission
Randomized, Multicenter, Phase 3 Study of Azacytidine (AZA) + Venetoclax as Maintenance Therapy in Patients With AML in Remissionin Younger Adults With Favorable-risk AML in First Remission After Conventional Chemotherapy
The First Affiliated Hospital of Soochow University
124 participants
Jun 25, 2022
INTERVENTIONAL
Conditions
Summary
This phase III trial is conducted to evaluate if azacitidine in combination with venetoclax as maintenance therapy improves relapse-free survival (RFS) for younger adults with favorable-risk acute myeloid leukemia (AML) who remained in first complete remission (CR1) following intensive consolidation.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Given SC
Given PO
Patients will receive disease monitoring and supportive care for any complication.
Locations(2)
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NCT05404906