RecruitingNCT05405673

Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia

A Prospective Cross-sectional Multi-center Study to Assess the Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia


Sponsor

Chinese University of Hong Kong

Enrollment

2,500 participants

Start Date

Jun 29, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The investigators aim to evaluate and compare the diagnostic accuracy of FIT and the novel panel of bacterial gene markers (Fn, m3, Ch and Bc) collectively named as M3, in detecting colorectal advanced neoplasia.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new stool-based (fecal) test that looks at specific bacterial markers to detect colorectal cancer or large precancerous polyps. It aims to see how accurately this test can find problems before a colonoscopy is performed. **You may be eligible if...** - You are 18 years or older - You are scheduled for a colonoscopy for cancer screening, polyp follow-up, or symptoms like anemia or changes in bowel habits - You are willing to provide written consent **You may NOT be eligible if...** - You have a condition that makes colonoscopy unsafe (e.g., bowel obstruction, unstable heart or lung problems) - You are on blood thinners that cannot be stopped, or have active gastrointestinal bleeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTFecal immunochemical test (FIT)

A kind of stool test


Locations(1)

Prince of Wales Hospital

Hong Kong, Hong Kong

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NCT05405673


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