RecruitingNCT05409794

Basal Plasma Lithium Levels and Suicidal Events

Basal Plasma Lithium Levels and Suicidal Events (LIPS)

Sponsor

University Hospital, Montpellier

Enrollment

158 participants

Start Date

Dec 9, 2022

Study Type

OBSERVATIONAL

Conditions

Major Depressive Disorder Bipolar Disorder Suicidal Behavior

Summary

Suicidal behavior is a major public health issue and there are currently no specific treatments for it. However, lithium, the reference treatment for bipolar disorder, have been shown to be effective in preventing suicidal risk. Apart from drug treatments, lithium is present in our environment and its levels varies from one individual to another, depending, especially, on diet. Knowing that patients with a mood disorder generally have a poor lifestyle and a less rich and varied diet than the general population, variations in basal lithium levels can be expected in these patients.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is exploring whether natural lithium levels in the blood (not from medication) are connected to the risk of suicidal thoughts or attempts in people experiencing a major depressive episode. It is an observational study, meaning researchers measure but do not treat. **You may be eligible if...** - You are 18 or older - You are currently experiencing a major depressive episode (as diagnosed by DSM-5 criteria) - You have not taken any lithium-based medication in the past 12 months - If being enrolled as a "suicide group": you have had a suicidal event in the past 12 months - If being enrolled as a "control group": you have had no suicidal events in the past 12 months **You may NOT be eligible if...** - You have ever been diagnosed with schizophrenia or schizoaffective disorder - You are pregnant or breastfeeding - You are legally restricted from making your own decisions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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