A Study of SHR-1501 Alone or in Combination With BCG or SHR-1316 in Subjects With NMIBC
Phase I/II Clinical Study of Dose Escalation and Dose Expansion of SHR-1501 Alone or in Combination With Bacille de Calmette Guerin (BCG) or SHR-1316 in the Treatment of Non-muscle Invasive Bladder Cancer(NMIBC)
Shanghai Hengrui Pharmaceutical Co., Ltd.
150 participants
Nov 23, 2022
INTERVENTIONAL
Conditions
Summary
The study is to evaluate the safety and tolerability of SHR-1501 alone or in combination with BCG or SHR-1316 in the patients with NMIBC, and to determine the RP2D of SHR-1501 in combination with BCG or SHR-1316. To evaluate the preliminary efficacy of SHR-1501 alone or in combination with BCG or SHR-1316 in the treatment of NMIBC.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
SHR-1501 single agent dose escalation, and in combination of BCG or SHR-1316.
Locations(1)
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NCT05410730