Autologous Testicular Tissue Transplantation
Autologous Testicular Tissue Transplantation for Fertility Restoration
Universitair Ziekenhuis Brussel
5 participants
Nov 22, 2024
INTERVENTIONAL
Conditions
Summary
Freezing testicular tissue of prepubertal boys is a method for preserving spermatogonial stem cells in case of imminent gonadotoxic treatment during childhood. In case of total azoospermia or absence of spermatozoa that can be used for intra-cytoplasmic injection (ICSI) in adulthood, the investigators intend to perform the first in men autologous testicular tissue transplantation to restore fertility.
Eligibility
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Interventions
Freezing testicular tissue of prepubertal boys is a method for preserving spermatogonial stem cells. If no spermatozoa suitable for ICSI are detected in the ejaculate, the investigators will perform autologous testicular tissue transplantation with the primary objective being to restore spermatogenesis and fertility.
Locations(1)
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NCT05414045