RecruitingNot ApplicableNCT05425615

Language Processing and TMS

Probing Language Processes Using Transcranial Magnetic Stimulation


Sponsor

Medical College of Wisconsin

Enrollment

135 participants

Start Date

Jun 5, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study will examine the effect of TMS on people with stroke and aphasia as well as healthy individuals.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria5

  • Diagnosed with left hemisphere stroke
  • Consent date \>= 1 month after stroke onset
  • Right-handed
  • Fluent in English
  • years of age or older

Exclusion Criteria18

  • Severe cognitive, auditory or visual impairments that would preclude cognitive and language testing
  • Non-decisional per decisionality questionnaire or other clinical assessment
  • Presence of major untreated or unstable psychiatric disease (e.g. schizophrenia, bipolar disease)
  • A chronic medical condition that is not treated or is unstable
  • Presence of
  • cardiac stimulators or pacemakers or intracardiac lines
  • neurostimulators
  • medication infusion device
  • any other implants near the scalp (e.g., cochlear implants) or in the eye
  • metal in the body
  • Pregnancy
  • History of skull fractures, or skin diseases
  • History of ongoing or unmanaged seizures or a family history of epilepsy
  • Presence of factors that potentially decrease seizure thresholds
  • On pro-convulsant medications
  • Untreated Sleep deprivation or insomnia
  • Ongoing alcoholism or illegal drug abuse (e.g., cocaine or MDMA users)
  • History of dyslexia or other developmental learning disabilities

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Interventions

DEVICETranscranial Magnetic Stimulation

Deymed DuoMag XT-100 rTMS


Locations(1)

Medical College of Wisconsin

Milwaukee, Wisconsin, United States

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NCT05425615


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