Aphasia Clinical Trials

61 recruiting

Aphasia Trials at a Glance

81 actively recruiting trials for aphasia are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 51 trials, with the heaviest enrollment activity in Philadelphia, Baltimore, and Toronto. Lead sponsors running aphasia studies include Changping Laboratory, Johns Hopkins University, and Medical College of Wisconsin.

Browse aphasia trials by phase

Treatments under study

About Aphasia Clinical Trials

Looking for clinical trials for Aphasia? There are currently 61 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Aphasia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Aphasia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 81 trials

Recruiting
Phase 2

Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia

StrokeAphasiaAphasia Following Cerebral Infarction
University of Pennsylvania63 enrolled1 locationNCT06968663
Recruiting
Not Applicable

Effects of Aphasia Identification Cards on Service Workers' Comprehension of People With Aphasia

Aphasia
University of Massachusetts, Amherst160 enrolled1 locationNCT06990997
Recruiting

The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech

Apraxia of SpeechPrimary Progressive AphasiaNon-fluent Aphasia+1 more
Mayo Clinic47 enrolled1 locationNCT03313011
Recruiting
Phase 2

Clinical Study of Neflamapimod in Patients With Primary Progressive Aphasia

Nonfluent Variant Primary Progressive Aphasia (nfvPPA)
EIP Pharma Inc20 enrolled7 locationsNCT07033481
Recruiting
Not Applicable

Long Term Effect of Brain Stimulation in PPA

Primary Progressive Aphasia(PPA)
Hospital San Carlos, Madrid80 enrolled1 locationNCT07158216
Recruiting
Not Applicable

Remotely-supervised Neuromodulation in PPA

Primary Progressive Aphasia(PPA)Progressive AphasiaProgressive Aphasia in Alzheimer's Disease+3 more
Maya Henry80 enrolled2 locationsNCT07260253
Recruiting
Not Applicable

Mirror Speech Entrainment: A Novel Technique for Voice Personalized Speech Entrainment for Nonfluent Aphasia

StrokeAphasiaAphasia Non Fluent
University of South Florida20 enrolled2 locationsNCT06829420
Recruiting
Not Applicable

Intervention for Communication Quality of Life in Primary Progressive Aphasia

Primary Progressive Aphasia(PPA)Progressive AphasiaLogopenic Progressive Aphasia (LPA)+9 more
Maya Henry30 enrolled1 locationNCT07219680
Recruiting
Phase 2

Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia

StrokeAphasia
University of Pittsburgh30 enrolled1 locationNCT05653440
Recruiting

Development and Validation of Language and Communication Assessment Scales

AphasiaLanguage Disorders
IRCCS San Camillo, Venezia, Italy50 enrolled1 locationNCT07518576
Recruiting
Not Applicable

Telerehabilitation for Aphasia (TERRA)

Stroke RehabilitationStrokeAphasia
University of South Carolina100 enrolled1 locationNCT04682223
Recruiting
Not Applicable

The Swedish BioFINDER 2 Study

DementiaMultiple System AtrophyAlzheimer Disease+10 more
Skane University Hospital2,950 enrolled2 locationsNCT03174938
Recruiting
Not Applicable

Effects of Neuronavigated Theta Burst Stimulation in Therapy of Post-stroke Aphasia

Stroke, IschemicAphasia Non Fluent
Institute of Psychiatry and Neurology, Warsaw45 enrolled1 locationNCT05303649
Recruiting
Not Applicable

Aphasia Physical EXercise Study: Randomized Trial

AphasiaAphasia, AcquiredAphasia, Fluent
University of California, Berkeley120 enrolled4 locationsNCT07281313
Recruiting
Not Applicable

Chinese-Specific Speech Imagery Coding Using High-Density ECoG

StrokeALSAphasia+5 more
Second Affiliated Hospital, School of Medicine, Zhejiang University50 enrolled1 locationNCT07460037
Recruiting
Not Applicable

Effects of Gesture Plus Verbal Treatment (GVT) in Cantonese Speakers With Aphasia

AphasiaGestures
Hong Kong University90 enrolled1 locationNCT07455162
Recruiting
Phase 2

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

StrokeAphasiaAphasia, Acquired+1 more
University of Pennsylvania24 enrolled1 locationNCT06842745
Recruiting

Language in Primary Progressive Aphasia

Primary Progressive Aphasia
Northwestern University500 enrolled1 locationNCT00537004
Recruiting

Speech and Language Interventions for Italian People With PPA

Primary Progressive Aphasia(PPA)
Istituti Clinici Scientifici Maugeri SpA30 enrolled2 locationsNCT06739967
Recruiting
Early Phase 1

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

Alzheimer DiseaseMild Cognitive ImpairmentLogopenic Progressive Aphasia+1 more
Massachusetts General Hospital30 enrolled1 locationNCT06538311