RecruitingNot ApplicableNCT05429827

The Therapeutic Effects of Dextrose Injection for Myofascial Pain Syndrome


Sponsor

National Cheng-Kung University Hospital

Enrollment

30 participants

Start Date

Nov 18, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Patients with an myofascial trigger point (MTrP) in their upper trapezius will be divided into three groups: Group A receiving MTrP injection with normal saline (control group), Group B with hypo-osmolar dextrose (5% dextrose), and Group C with hyper-osmolar dextrose (15% dextrose). Clinical outcomes and morphological changes will be measured before the injection, one hour after, one week after, two weeks after, and one month after the injection to delineate the therapeutic effects of dextrose injection for an MTrP.


Eligibility

Min Age: 20 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether injecting dextrose (a type of sugar water) into painful muscle knots — called myofascial trigger points — in the neck and upper back can reduce pain. This technique is called prolotherapy or dextrose injection. Researchers want to compare how well it works versus other standard treatments for myofascial pain syndrome. You may be eligible if... - You are 20 years of age or older - You have been diagnosed with myofascial pain syndrome (MPS) with a confirmed trigger point in your neck or upper back (upper trapezius muscle) - Your symptoms have been present for more than 3 weeks - You can communicate and understand the study instructions You may NOT be eligible if... - You have a serious medical condition, bleeding disorder, or are on blood thinners - You have a cognitive impairment or psychiatric disorder - You have hepatitis B or HIV/AIDS - You have cancer or diabetes - You are pregnant or may be pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERnormal saline

Inject 2 ml normal saline into a myofascial trigger point and evaluate the clinical effects before and after the injection.

DRUGDextrose 5% in water

Inject 2 ml 5% dextrose into a myofascial trigger point and evaluate the clinical effects before and after the injection.

DRUGDextrose 15% in water

Inject 2 ml 15% dextrose into a myofascial trigger point and evaluate the clinical effects before and after the injection.


Locations(1)

Department of physical Medicine and Rehabilitation, National Cheng Kung University Hospital

Tainan, Taiwan

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NCT05429827


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