RecruitingPhase 3NCT05437575

Prehospital Analgesia INtervention Trial (PAIN)

Sponsor

Jason Sperry

Enrollment

994 participants

Start Date

Nov 27, 2023

Study Type

INTERVENTIONAL

Conditions

Traumatic Injury

Summary

The Prehospital Analgesia INtervention trial (PAIN) is a proposed 4 year (3-year enrollment) multicenter, prehospital, randomized, double-blind, clinical trial that will enroll approximately 994 patients at select LITES Network sites. The objective is to perform a prospective, interventional, randomized trial among prehospital trauma patients with compensated shock (SI≥0.9 or HR ≥115) and an indication for pain management, comparing patient centered outcomes following prehospital administration of ketamine hydrochloride versus fentanyl citrate.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Fentanyl Citrate and a drug called Ketamine Hydrochloride for people with traumatic injury. The study is currently recruiting participants at 11 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGKetamine Hydrochloride

ketamine hydrochloride 2.5mg/ml packaged in pre-filled syringe

DRUGFentanyl Citrate

fentanyl citrate 10mcg/ml packaged in pre-filled syringe

Locations(11)

University of California, San Diego

San Diego, California, United States

Zuckerberg San Francisco General Hospital

San Francisco, California, United States

Cooper University Health Care

Camden, New Jersey, United States

Atrium Health and Carolinas Medical Center

Charlotte, North Carolina, United States

University of Cincinnati

Cincinnati, Ohio, United States

Allegheny Health Network (AHN) Allegheny General Hospital

Pittsburgh, Pennsylvania, United States

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

Guthrie Robert Packer Hospital

Sayre, Pennsylvania, United States

University of Utah

Salt Lake City, Utah, United States

The University of Vermont Larner College of Medicine

Burlington, Vermont, United States

Medical College of Wisconsin

Milwaukee, Wisconsin, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT05437575

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