RecruitingPhase 2NCT05442632

Efficacy and Safety of Herombopag in Patients With Thrombocytopenia Before Hepatectomy

Director, Department of Liver Surgery, Fudan University Shanghai Cancer Center


Sponsor

Fudan University

Enrollment

96 participants

Start Date

Jul 25, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This is a single center, randomized, controlled study, to evaluate the efficacy and safety of Herombopag in patients with Thrombocytopenia before hepatectomy.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing herombopag, a drug that helps increase platelet counts, in patients who have low platelets (thrombocytopenia) and are scheduled for liver surgery (hepatectomy). The goal is to see if raising platelet levels before surgery is safe and effective. **You may be eligible if...** - You are 18 years or older - You are scheduled to undergo liver surgery (hepatectomy) - Your platelet count is between 50 and 80 billion per liter (mildly low) - Your liver function is preserved (Child-Pugh A or mild B) - Your life expectancy is at least 3 months - Your bone marrow and kidney function are normal **You may NOT be eligible if...** - You have had a blood clot (arterial or venous thrombosis) in the past - You have a primary blood disorder or a history of immune thrombocytopenia (ITP) - You have received a platelet transfusion within the past 7 days - You have a history of certain cancers of the blood Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGHetrombopag

The patients received Hetrombopag 5mg orally d1-14 days, surgery will be conducted at d6-14 day

DRUGPlacebo

The patients received Placebo 5mg orally d1-14 days, surgery will be conducted at d6-14 day


Locations(1)

Fudan University Shanghai Cancer Center

Shanghai, China

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NCT05442632