RecruitingNot ApplicableNCT05447416

Intermittent Hypoxic Training (IHT) Versus Hyperbaric Oxygen Therapy (HBOT) for Aerobic Performance

Intermittent Hypoxic Training (IHT) Versus Hyperbaric Oxygen Therapy (HBOT) for Aerobic Performance - Prospective Randomized Study


Sponsor

Assaf-Harofeh Medical Center

Enrollment

66 participants

Start Date

Jun 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Comparing the effect of HBOT and IHT on aerobic performance of athletes.


Eligibility

Sex: MALEMin Age: 18 YearsMax Age: 45 Years

Inclusion Criteria4

  • Vo2max above 3500 ml or Vo2max/kg above 50 ml/kg
  • Age 18-45
  • Subjects are active aerobic athletes, training regularly more than 4 exercise sessions per week.
  • Subject willing and able to read, understand and sign an informed consent

Exclusion Criteria12

  • Inability to attend scheduled clinic visits and/or comply with the study protocol
  • Active malignancy
  • Active smokers
  • Previous treatment of HBOT for any reason prior to study enrollment.
  • Chest pathology incompatible with pressure changes
  • Major orthopedic injury at the past 3 months
  • Inner ear disease
  • Lung pathology
  • The inability to perform an awake brain MRI
  • Claustrophobia
  • Previous neurologic conditions (e.g., Epilepsy, Brain tumors or s/p neurosurgery etc.)
  • Comorbidities and medications that rule out the subject

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Interventions

DEVICEHyperbaric Oxygen Therapy - HBOT

Each session will include exposure of 90 minutes to 100% at 2 ATA, with 5 minutes air breaks every 20 minutes

DEVICEIntermittent Hypoxic Training - IHT

Each session lasts 60 minutes of 15.2% oxygen at 1.0 ATA. Subjects will be training according to individualized training protocol.


Locations(1)

The Sagol Center for Hyperbaric Medicine and Research Shamir Medical Center (Assaf Harofeh)

Zrifin, Israel

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NCT05447416