Providing Oxygen During Intubation in the NICU Trial

This study looks at whether providing oxygen during the process of placing a breathing tube (intubation) in premature babies in the NICU improves safety and outcomes. Intubation can cause a drop in oxygen levels, and this trial tests whether giving supplemental oxygen during the procedure helps. You may be eligible if: - Your baby is 28 weeks gestational age or older - Your baby is in the NICU and needs to be intubated - Pre-medications including a paralytic were given before the procedure You may NOT be eligible if: - Your baby has a known difficult or abnormal airway - Your baby has unstable vital signs or is being actively resuscitated - Oxygen levels could not be raised to 90% or above before the attempt - The intubation is being done by a non-NICU provider (e.g., anesthesiology or ENT) - Your baby has an unrepaired congenital diaphragmatic hernia, tracheoesophageal fistula within 2 weeks of repair, or a tracheostomy - Your baby has previously been enrolled in this trial - Your baby is undergoing nasal intubation - Your baby has tested positive for COVID-19 or is under investigation - Your baby has cyanotic heart disease, is on ECMO support, or is a conjoined twin Talk to your doctor to see if this trial is right for you.