RecruitingNot ApplicableNCT05457140

Multiomic Diagnostics in Youth With Psychosis

Multiomic Diagnostics in Child and Adolescent Psychosis

Sponsor

Rady Pediatric Genomics & Systems Medicine Institute

Enrollment

15 participants

Start Date

Oct 10, 2022

Study Type

INTERVENTIONAL

Conditions

Psychosis

Summary

Rady Children's Institute for Genomic Medicine seeks to understand the genomes and immune systems in 15 children and adolescents who are admitted to Rady Children's Hospital Child and Adolescent Psychiatry Service with psychotic symptoms or schizophrenia. Cutting-edge genome and protein sequencing technology will be used to better understand how immunological and genetic assessments may improve our ability to identify the cause of psychosis and impact care. The investigator also hopes to identify new genetic and/or autoimmune causes of psychosis that may inform new treatment for future patients.

Eligibility

Min Age: 7 YearsMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This study collects genetic and biological samples from children and adolescents admitted to hospital for a first episode of psychosis (loss of touch with reality, hearing voices, or severe paranoia), along with samples from their biological parents, to look for genetic causes and biological patterns that could improve diagnosis and treatment. **You may be eligible if...** - You are a child or adolescent admitted to Rady Children's Hospital with a first episode of psychosis - OR you are the biological parent of an enrolled child participant - You are able to provide informed consent or assent **You may NOT be eligible if...** - The child or adolescent has already had whole genome or exome sequencing done previously - The family cannot be approached for enrollment - Informed consent cannot be obtained - You are a family member who is known not to be genetically related to the patient Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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