Clinical Study on the Re-irradiation of Lateral Pelvic Recurrences of Gynecological Malignancies
Phase II Clinical Study on the Re-irradiation of Lateral Pelvic Recurrences of Gynecological Malignancies
CNAO National Center of Oncological Hadrontherapy
55 participants
Feb 24, 2021
INTERVENTIONAL
Conditions
Summary
The study aims to obtain a local control rate in patients with lateral pelvic relapses of gynecologycal cancers previously irradiated. High LET (Linear Energy Transfer) particles as carbon ions can guarantee a biologic advantage compared to photons in radioresistant neoplasms, given to their higher biological efficacy (RBE).
Eligibility
Plain Language Summary
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Interventions
CIRT: Planning Target Volume (PTV) will be delivered a total dose of 48-52.8 GyRBE in 12 fractions, 4 fractions per week. Treatment duration 3 weeks. Treatment lasting more than 5 weeks or cases of treatment with less than 6 fractions in 14 consecutive days will not be accepted.
Locations(1)
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NCT05457595