RecruitingNCT05459597

Antiepileptic Drugs in Elderly Patients

Population Pharmacokinetics, Effectiveness and Safety of Antiepileptic Drugs in Elderly Patients


Sponsor

Wei Zhao

Enrollment

500 participants

Start Date

Jan 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose is to study the population pharmacokinetics, effectiveness and safety of antiepileptic drug (phenytoin, carbamazepine, lamotrigine, levetiracetam, parempanel, etc) in elderly patients and recommend optimized dosage regimens.


Eligibility

Min Age: 65 YearsMax Age: 100 Years

Inclusion Criteria3

  • Age ≥65 years old;
  • Diagnosed with epilepsy;
  • Using antiepileptic drugs for treatment;

Exclusion Criteria4

  • Patients who are expected to die within 48 hours;
  • Patients with allergy to antiepileptic drugs;
  • Patients receiving other investigational drugs;
  • Other factors that the researcher considers unsuitable for inclusion.

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Interventions

DRUGantiepileptic drugs

phenytoin, carbamazepine, lamotrigine, levetiracetam, perampanel, etc. as part of routine treatment.


Locations(1)

Wei Zhao

Jinan, Shandong, China

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NCT05459597


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