RecruitingNCT05466396

Lung Health of Early COPD: A Multi-center Cohort Study

Lung Health of Early Chronic Obstructive Pulmonary Disease: A Multi-center Cohort Study

Sponsor

Ting YANG

Enrollment

1,550 participants

Start Date

Aug 1, 2022

Study Type

OBSERVATIONAL

Conditions

COPD

Summary

This is a multi-center, prospective, cohort study in early COPD patients. This study aims to elucidate the lung function decline and its association with smoking and other risk factors. Other biomarkers and image markers from chest CT scan are also analyzed to investigate the lung function in early COPD patients.

Eligibility

Min Age: 35 YearsMax Age: 75 Years

Inclusion Criteria3

Gender: male or female
Age: 35-75 years old
post-bronchodilator spirometry: FEV1/FVC \< 0.8 and FEV1%pred ≥80%

Exclusion Criteria5

Other diseases may affect lung function, like lung cancer, bronchiectasis, interstitial lung disease or chest surgery.
BMI \> 35 kg/m2
Dementia or other severe neurological disease
Pregnancy
Conditions that contraindicated lung function test