RecruitingNCT05485077

A Prospective Cohort Study on Colorectal Cancer Screening in Community Population

Colorectal Cancer Screening Cohort Study in Shougang Community Population Based on Polygene Methylation Detection Technology


Sponsor

Singlera Genomics Inc.

Enrollment

18,000 participants

Start Date

Jul 9, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This study will validate the real world results of polygene methylation detection in colorectal cancer in a large prospective community cohort. In this study, questionnaire survey and polygene methylation detection technology of colorectal cancer were used as preliminary screening methods, and colonoscopy was used as further validation examination method to screen colorectal cancer and precancerous lesions. The diagnosis and outcome of all lesions were based on colonoscopy and pathological examination.


Eligibility

Min Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This is a long-term screening study following people in the community to understand the risk factors for colorectal cancer (bowel cancer). Participants will complete health questionnaires and be followed over time to see who develops colorectal cancer and what factors are associated with it. **You may be eligible if...** - You are 40 years old or older - You have full decision-making capacity - You are willing and able to complete annual follow-up interviews - You are able to share information about any cancer diagnosis from other hospitals with the research team **You may NOT be eligible if...** - You have a personal history of colorectal cancer or another active cancer - You have had part of your colon or rectum removed previously - You are currently receiving cancer treatment - You have had major surgery or a blood transfusion/transplant in the past 3 months - You are pregnant or breastfeeding - You have an autoimmune disease, hereditary condition, or serious mental illness Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Peking University Shougang Hospital

Beijing, Beijing Municipality, China

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NCT05485077


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