RecruitingPhase 3NCT05486468

The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment

The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment (TYNI Trial)


Sponsor

Texas Retina Associates

Enrollment

30 participants

Start Date

Oct 5, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The Use of Two YUTIQ versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment (TYNI Trial)


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether two YUTIQ implants (tiny, long-acting steroid devices placed in the eye) work better than a sham procedure in treating chronic non-infectious uveitis — a painful inflammation in the back of the eye that can lead to vision loss if untreated. You may be eligible if: - You are 18 or older and in good general health - You have chronic non-infectious uveitis affecting the back part of the eye - Your condition previously responded to corticosteroid treatment but came back (indicating chronicity) - Your eye inflammation is currently active You may NOT be eligible if: - You are pregnant or breastfeeding - You have only had anterior (front-of-eye) uveitis with no posterior involvement - Your uveitis has an infectious cause - You have glaucoma that is not well-controlled on 2 or fewer medications - You have had eye surgery within the past 12 weeks - You have a known allergy to YUTIQ components Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGYutiq 0.18 MG Drug Implant

YUTIQ ® (fluocinolone acetonide intravitreal implant) 0.18 mg, for intravitreal injection

OTHERSham Injection

Sham injection


Locations(1)

Texas Retina Associates

Plano, Texas, United States

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NCT05486468


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