Comparison Of Reduced DAPT Followed by P2Y12 Inhibitor Monotherapy With Prasugrel vs stAndard Regimen in STEMI Patients

After a STEMI heart attack treated with a stent, patients typically take two blood-thinning medications (dual antiplatelet therapy, or DAPT) for 12 months. This study tests whether switching to a single blood thinner (prasugrel alone) after just 30–45 days is as effective but causes less bleeding compared to the full 12-month dual therapy. You may be eligible if: • You had a STEMI (ST-elevation myocardial infarction) treated with a stent (PCI) • You completed the initial 30–45 days of dual antiplatelet therapy without any major events or regimen changes • Your stent was successfully placed (less than 30% residual blockage) • You provided informed consent You may NOT be eligible if: • You are on oral anticoagulation (blood thinners like warfarin) • You have had a stroke or transient ischemic attack in the past 12 months • You have severe liver failure (Child-Pugh C) or severe kidney impairment (creatinine clearance below 30) • You are pregnant, recently gave birth (within 90 days), or breastfeeding • You had an out-of-hospital cardiac arrest (unless from a treatable arrhythmia with full recovery) • You are in cardiogenic shock Talk to your doctor to see if this trial is right for you.