Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects
Non-randomized Pilot Study to Characterize Temporo-masseteric Nerve Block (TMNB) in
Rutgers, The State University of New Jersey
20 participants
Oct 10, 2022
INTERVENTIONAL
Conditions
Summary
The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter muscles, at rest and clench, before and after unilateral TMNB injection, will be the primary outcome measures. Post-injection assessments will be performed at 30 minutes, 2 hours, and 2 weeks after the injection. Participants will be surveyed regarding their experience receiving the TMNB injection (secondary outcomes).
Eligibility
Inclusion Criteria15
- years of age
- All ethnicity
- Male and female sex
- Fluent in written/spoken English
- Never been diagnosed with TMD
- No significant history of orofacial pain
- \<5 headaches/month in the 3 months before enrollment
- No reported use of a nightguard or occlusal splint 'No' to all questions on self-administered questionnaire for TMD screening:
- Pain in jaw or temple on either side of the face in the last 30 days
- Stiffness or pain in jaw upon awakening in the last 30 days
- Any pain increase/reduction in the jaw/temple region during the last 30 days with
- Chewing hard or tough food
- Opening mouth or moving jaw forward or to the side
- Hold teeth together/clenching/grinding/chewing gum
- Using the jaw during activities such as talking, kissing or yawning
Exclusion Criteria12
- Traumatic injury/ surgery on face or jaw \< 6 months
- current orthodontic treatment
- pregnant or nursing,
- kidney failure or renal dialysis,
- heart disease or heart failure,
- uncontrolled chronic respiratory disease/ hypertension/ diabetes
- history of
- seizures
- hyperthyroidism
- drug or alcohol abuse
- psychiatric disorder/conditions requiring hospitalization
- chemotherapy/radiation
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Interventions
The TMNB injection is a local anesthetic injection technique that targets the anterior deep temporal and masseteric branches of the mandibular division of the Trigeminal Nerve. The surface landmark for the twin block injection site is located by palpating for the depression created by the greater wing of the sphenoid bone at the superior border of the zygomatic process and approximately 1 cm posterior to the posterior border of the frontal process of the zygomatic bone. This site is first disinfected with alcohol wipes prior to inserting a 27- or 25-gauge long dental needle (32 mm). Angled 35-45° away from the calvarium (skull) and perpendicular to the zygomatic arch (along the coronal plane), the needle is advanced to its length before injecting 1.8 mL of 2% lidocaine with 1:100,000 epinephrine.
Locations(1)
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NCT05507164