RecruitingNot ApplicableNCT05509959

Women SHINE: Addressing Syndemics and HIV Among Women Through Tech-Based Peer Engagement


Sponsor

University of California, San Diego

Enrollment

360 participants

Start Date

Nov 15, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

A two-arm RCT will be conducted to test the efficacy of Women SHINE, a web-based trauma-informed peer navigation-social support intervention (Figure 2). A total of 360 women living with HIV/AIDS (WLHA) with a history of adulthood interpersonal violence who have been prescribed ART but are non-adherent (\< 90% ART adherent in the last 4 weeks) will be enrolled in the study. WLHA will be randomized (1:1) into one of the following conditions: 1) Women SHINE intervention arm (n=180) or 2) Control arm (n=180). The Women SHINE intervention arm will receive a four-month intervention including peer navigator (PN) one-on-one sessions, phone/text-based check-ins, 7 psychoeducation weekly support group sessions (120 mins.) co-facilitated by a licensed therapist and PN, and access to a static website with resources for HIV care, interpersonal violence, trauma, mental health, and substance use. The control arm will receive one group session (60 mins.) on self-care and well-being and access to the aforementioned website with resources. Women will complete a video-based survey and mailed hair sample self-collection at baseline, 4-, 8-, and 12-months post-randomization, to evaluate improvements in ART adherence (Aim 1), emotion regulation, and PTSD symptoms (Aim 2). Investigators will examine the mediating effect of individual (retention in HIV care, coping self-efficacy, social support, ancillary support services use) and socio-structural (stigma, medical mistrust) mechanisms of change on the efficacy of Women SHINE (Aim 3).


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria9

  • Cisgender female
  • Diagnosis of HIV by a physician, healthcare provider, or community health worker
  • Aged 18 years or older
  • Speaking and reading English or Spanish
  • Adulthood experiences of interpersonal violence
  • Currently prescribed ART
  • Self-report of \<90% past-month ART adherence
  • Not currently participating in another adherence intervention
  • Access to an internet browser

Exclusion Criteria12

  • Unwillingness to participate in the intervention
  • Transgender female
  • No diagnosis of HIV by a physician, healthcare provider, or community health worker
  • Aged less than 18 years
  • Not speaking and reading English or Spanish
  • Not currently prescribed ART
  • Self-report of \>= 90% past-month ART adherence
  • Currently participating in another adherence intervention
  • No access to an internet browser
  • Cognitive impairment limiting the ability to provide informed consent
  • Experiencing only childhood experiences of interpersonal violence
  • Inability to safely participate in the study based on secondary screener

Interventions

BEHAVIORALWomen SHINE

Minimum of nine weekly one-on-one peer navigation sessions and 7 weekly psychoeducation support group sessions.

BEHAVIORALControl

Single group session and access to website


Locations(1)

The Regents of the Univ. of Calif., U.C. San Diego

La Jolla, California, United States

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NCT05509959


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