RecruitingNCT05513820

Automatic Detection in MRI of Prostate Cancer: DAICAP


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

1,250 participants

Start Date

Jun 21, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Prostate cancer is the most common cancer in France and the 3rd most common cancer death in humans. The introduction of pre-biopsy MRI has considerably improved the quality of prostate cancer (PCa) diagnosis by increasing the detection of clinically significant PCa , and by reducing the number of unnecessary biopsies.However the diagnostic performance of Prostate MRI is highly dependent on reader experience that limits the population based delivery of high quality multiparametricMRI (mpMRI) driven PCa diagnosis. The main objective of this study is the development and the test of diagnostic accuracy of an AI algorithm for the detection of cancerous prostatic lesions from mpMRI images. The secondary objective is the development and the test of diagnostic accuracy of an AI algorithm to predict tumor aggressiveness from mpMRI images.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

The DAICAP study is developing and testing an AI system that reads prostate MRI scans to help detect prostate cancer. The study has two parts: one looking back at existing patient records (retrospective) and one that will enroll new patients going forward (prospective). The goal is to reduce missed cancers and unnecessary biopsies. **You may be eligible if...** - You have elevated PSA or an abnormal rectal exam raising suspicion of prostate cancer - You are scheduled for — or have previously had — an MRI and biopsy of the prostate as standard diagnostic care - You have not been previously diagnosed with prostate cancer or treated for it **You may NOT be eligible if...** - You have already been diagnosed with prostate cancer and received treatment before the diagnostic MRI workup - Your MRI images are incomplete or unusable due to artifacts - You are unable or unwilling to provide consent (for the prospective part) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

La Pitié Salpétrière Hospital

Paris, France

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NCT05513820