Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
Use of Viscoelastic Assays Beyond Coagulation: Pre- and Post-operative TEG
University of Colorado, Denver
400 participants
Jun 26, 2022
OBSERVATIONAL
Conditions
Summary
The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease burden, cancer recurrence and overall survival as well as thrombotic and hemorrhagic post-operative complications. The investigators further hypothesize that there is histologic pathology correlates to pre-operative TEG abnormalities, and that it identifies patients with virulent tumor biology.
Eligibility
Inclusion Criteria2
- new diagnosis by the providing physician of hepatopancreaticobiliary, esophageal, colorectal or lung adenocarcinoma will be eligible for enrollment in the study
- Years and older
Exclusion Criteria5
- Under 18 years old
- prisoners
- those unable to provide informed consent
- pregnant women
- and those undergoing emergent or urgent operative intervention at the time of diagnosis
Interventions
Blood samples
Locations(1)
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NCT05517811