RecruitingNCT05517811

Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection

Use of Viscoelastic Assays Beyond Coagulation: Pre- and Post-operative TEG

Sponsor

University of Colorado, Denver

Enrollment

400 participants

Start Date

Jun 26, 2022

Study Type

OBSERVATIONAL

Conditions

Liver Cancer Colorectal, Cancer Esophageal Cancer Pancreas Cancer Lung Adenocarcinoma Biliary Cancer Control

Summary

The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease burden, cancer recurrence and overall survival as well as thrombotic and hemorrhagic post-operative complications. The investigators further hypothesize that there is histologic pathology correlates to pre-operative TEG abnormalities, and that it identifies patients with virulent tumor biology.

Eligibility

Min Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This study is measuring how blood clotting patterns (using a test called TEG) change before and after surgery in patients with certain cancers, specifically to understand whether cancer affects clotting in ways that matter during surgery. **You may be eligible if...** - You are 18 years or older - You have a new diagnosis of liver, pancreas, bile duct, esophageal, colorectal, or lung adenocarcinoma - You are scheduled for surgery related to this diagnosis **You may NOT be eligible if...** - You are under 18 years old - You are pregnant - You are unable to give informed consent - You are a prisoner - You need emergency or urgent surgery at the time of diagnosis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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