Liver Cancer Clinical Trials

99 recruiting

Liver Cancer Trials at a Glance

130 actively recruiting trials for liver cancer are listed on ClinicalTrialsFinder across 6 cities in 27 countries. The largest study group is Not Applicable with 26 trials, with the heaviest enrollment activity in Beijing, Guangzhou, and Chengdu. Lead sponsors running liver cancer studies include West China Hospital, Second Affiliated Hospital of Guangzhou Medical University, and Sun Yat-sen University.

Browse liver cancer trials by phase

Treatments under study

About Liver Cancer Clinical Trials

Looking for clinical trials for Liver Cancer? There are currently 99 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Liver Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Liver Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 130 trials

Recruiting

DESTINY-PANTUMOUR04

Liver CancerEsophageal CancerPancreatic Cancer+24 more
AstraZeneca100 enrolled17 locationsNCT07124000
Recruiting
Phase 1Phase 2

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Advanced Liver Cancers
Hoffmann-La Roche518 enrolled33 locationsNCT04524871
Recruiting
Phase 1

PD-1 mRNA LNP Vaccine for Advanced Primary Hepatocellular Carcinoma.

Liver Cancer
West China Hospital9 enrolled2 locationsNCT07053072
Recruiting

Collection of Blood From Patients With Cancer

Breast CancerLiver CancerProstate Cancer+2 more
National Cancer Institute (NCI)1,750 enrolled1 locationNCT00034216
Recruiting

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Liver NeoplasmsPrimary Liver CancerSecondary Liver Cancer+2 more
HistoSonics, Inc.5,000 enrolled27 locationsNCT06486454
Recruiting
Not Applicable

Electrochemotherapy (ECT) in Patients With Primary Visceral Tumors and/or Secondary Visceral Localizations, of Any Histotype

Liver CancerMelanomaMerkel Cell Carcinoma+9 more
Istituto Oncologico Veneto IRCCS24 enrolled1 locationNCT06753136
Recruiting

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

Breast CancerLiver CancerProstate Cancer+2 more
National Cancer Institute (NCI)750 enrolled1 locationNCT00451022
Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

CholangiocarcinomaHepatocellular CarcinomaHepatic Carcinoma+4 more
City of Hope Medical Center400 enrolled5 locationsNCT06342414
Recruiting
Phase 1

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-011 in Patients With Advanced Solid Tumor

Advanced Liver Cancer
Abbisko Therapeutics Co, Ltd200 enrolled32 locationsNCT04906434
Recruiting
Phase 1

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Liver CancerRhabdomyosarcomaWilms Tumor+3 more
Baylor College of Medicine24 enrolled1 locationNCT04715191
Recruiting
Phase 1Phase 2

Dual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCC

Metastatic Liver CancerAdvanced Hepatocellular Carcinoma (HCC)
Beijing Biotech30 enrolled1 locationNCT07500220
Recruiting

Cancer Loyalty Card Study 2 (CLOCS-2)

Liver CancerPancreatic CancerOvarian Cancer+7 more
Imperial College London2,900 enrolled1 locationNCT06447064
Recruiting
Phase 2

Radioembolization With Intra-arterial Angiotensin II to Improve Tumor-absorbed Dose (RADIANT)

Liver Cancer (Locally Advanced or Metastatic)
Niek Wijnen15 enrolled1 locationNCT07312292
Recruiting

Optimizing Y90 Therapy for Radiation Lobectomy

Metastatic CancerHCCResection+2 more
Northwestern University104 enrolled2 locationsNCT04390724
Recruiting

cfDNA Methylation for Liver Cancer Recurrence Detection

Primary Liver Cancer
Wuhan Ammunition Life-tech Co., Ltd500 enrolled1 locationNCT07466602
Recruiting

Early Detection of Liver Cancer by QUS

Liver CancerHepatocellular Carcinoma
Centre hospitalier de l'Université de Montréal (CHUM)328 enrolled1 locationNCT06345508
Recruiting
Not Applicable

Feasibility Study of CBCT for IGRT in Cancer Patients

Breast CancerLiver CancerHead and Neck Cancers+3 more
Varian, a Siemens Healthineers Company50 enrolled4 locationsNCT06681233
Recruiting
Not Applicable

FAST-IRM for HCC suRveillance in pAtients With High risK of Liver Cancer.

Liver CancerHepatocellular CarcinomaCirrhosis+1 more
Assistance Publique - Hôpitaux de Paris944 enrolled1 locationNCT05095714
Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Breast CancerLiver CancerEsophageal Cancer+35 more
UMC Utrecht8,000 enrolled18 locationsNCT04075305
Recruiting

Development and Testing of a Patient-facing Educational Tool About Liver Cancer Prevention

Liver Cancer
M.D. Anderson Cancer Center40 enrolled1 locationNCT07010315