Liver Cancer Clinical Trials

150 recruitingLast updated: June 17, 2026

There are 150 actively recruiting liver cancer clinical trials across 28 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1. Top locations include Beijing, Beijing Municipality, China, Guangzhou, Guangdong, China, Shanghai, Shanghai Municipality, China. Updated daily from ClinicalTrials.gov.


Liver Cancer Trials at a Glance

150 actively recruiting trials for liver cancer are listed on ClinicalTrialsFinder across 6 cities in 28 countries. The largest study group is Not Applicable with 31 trials, with the heaviest enrollment activity in Beijing, Guangzhou, and Shanghai. Lead sponsors running liver cancer studies include West China Hospital, Second Affiliated Hospital of Guangzhou Medical University, and Sun Yat-sen University.

Browse liver cancer trials by phase

Treatments under study

About Liver Cancer Clinical Trials

Looking for clinical trials for Liver Cancer? There are currently 112 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Liver Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Liver Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 150 trials

Recruiting
Phase 2

Y-90 Treatment Response Using Transarterial Radioembolization

Liver CancerHepatocellular CarcinomaPrimary Liver Cancer+3 more
Thomas Jefferson University30 enrolled1 locationNCT07145801
Recruiting

mSEPT9 Biomarker for Predicting Hepatocellular Carcinoma Occurrence in Patients With Cirrhosis

CirrhosisHepatocellular Carcinoma (HCC)Epigenomics+1 more
Central Hospital, Nancy, France400 enrolled1 locationNCT06778317
Recruiting
Not Applicable

Erector Spinae Plane Block Versus Thoracic Epidural Analgesia for Open Liver Resection

Liver CancerLiver NeoplasmsHepatic Resection
Nguyen Toan Thang60 enrolled1 locationNCT07642336
Recruiting
Phase 1Phase 2

GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

Hepatocellular CarcinomaMetastatic Liver CancerLiver Cancer, Adult+1 more
Eureka Therapeutics Inc.60 enrolled8 locationsNCT04864054
Recruiting

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

Breast CancerLiver CancerProstate Cancer+2 more
National Cancer Institute (NCI)750 enrolled1 locationNCT00451022
Recruiting

Prospective Clinical Database Construction for Liver Cancer Diagnosis and Treatment

Liver Cancer (Primary and Metastatic)
Tongji Hospital800 enrolled1 locationNCT07587216
Recruiting

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Liver NeoplasmsPrimary Liver CancerSecondary Liver Cancer+2 more
HistoSonics, Inc.5,000 enrolled30 locationsNCT06486454
Recruiting

Collection of Blood From Patients With Cancer

Breast CancerLiver CancerProstate Cancer+2 more
National Cancer Institute (NCI)1,750 enrolled1 locationNCT00034216
Recruiting

DESTINY-PANTUMOUR04

Liver CancerEsophageal CancerPancreatic Cancer+24 more
AstraZeneca100 enrolled17 locationsNCT07124000
Recruiting
Phase 1

A Phase 1 Trial of ERX-315 in Participants With Advanced Solid Tumors

Metastatic Breast CancerAdvanced Solid TumorMetastatic Ovarian Cancer+3 more
EtiraRx Australia Pty Ltd36 enrolled5 locationsNCT06533332
Recruiting
Phase 2Phase 3

Trop2-targeted immunoPET Imaging of Solid Tumors

Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Not Applicable

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

Liver CancerEsophageal CancerColon Cancer+7 more
Case Comprehensive Cancer Center200 enrolled1 locationNCT06263088
Recruiting
Phase 1Phase 2

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Advanced Liver Cancers
Hoffmann-La Roche518 enrolled33 locationsNCT04524871
Recruiting

LEARN: Learning Environment for Artificial Intelligence in Radiotherapy New Technology

Breast CancerLiver CancerPancreatic Cancer+6 more
University of Sydney300 enrolled4 locationsNCT05184790
Recruiting

China Metastatic Liver Cancer Clinical Registry Cohort Database

Liver CancerLiver MetastasesNeoplasms+3 more
Anhui Provincial Hospital2,000 enrolled3 locationsNCT07602504
Recruiting
Phase 1

Brodalumab in the Treatment of Immune-Related Adverse Events

Breast CancerLiver CancerEsophageal Cancer+15 more
Brian Henick, MD11 enrolled1 locationNCT06673329
Recruiting
Phase 2

68Ga-PSMA-11 PET-directed Radioligand Therapy in Metastatic Hepatocellular Carcinoma (HCC)

Liver CancerHepatocellular CarcinomaMetastatic Liver Cancer
Melissa Lumish10 enrolled1 locationNCT06852820
Recruiting

Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women

Breast CancerLiver CancerGastric Cancer+9 more
Washington University School of Medicine10 enrolled1 locationNCT06904365
Recruiting

4D-MRI for Precision Medicine

Liver CancerLung CancerHealthy Volunteers
University of Virginia100 enrolled1 locationNCT04657042
Recruiting

Integrated Cancer Repository for Cancer Research

Breast CancerLiver CancerEsophageal Cancer+47 more
University of Nebraska999,999 enrolled42 locationsNCT02012699