An Examination of Brown Adipose Tissue and Energy Expenditure in Infants
Pennington Biomedical Research Center
60 participants
Aug 17, 2022
OBSERVATIONAL
Conditions
Summary
Excess fetal adipose tissue growth during intrauterine development increases future obesity risk. Development of brown adipose tissue, a highly thermogenic organ in utero, may affect postnatal energy expenditure, thus influencing obesity risk. This pilot research study is designed to understand the developmental origins of energy balance by examining maternal and neonatal factors that influence neonatal brown adipose tissue and to quantify its physiological relevance to energy expenditure in human neonates.
Eligibility
Inclusion Criteria2
- aged 0 weeks to less than 3 weeks at visit 1
- be willing to complete MRI procedures
Exclusion Criteria5
- Unable to complete two clinic visits within 14 days
- Born with health conditions that would render the procedures unsafe
- Born earlier than 36 and 0 days gestation
- Taken a steroid drug since birth
- Implanted metal or electronic objects that render MRI unsafe
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05517967