Reducing Blood Pressure in Mid-life Adult Binge Drinkers

This study is looking at how different patterns of alcohol consumption — from no drinking to moderate drinking to binge drinking — affect blood pressure in middle-aged adults. Researchers want to understand the relationship between alcohol and cardiovascular health in people aged 50 to 64. You may be eligible if: - You are a man or woman between 50 and 64 years old - You do not drink alcohol, drink moderately, or binge drink - If you are female, you must be postmenopausal (no period for at least 1 year) - You can speak and understand English You may NOT be eligible if: - You have a history of diabetes, heart disease, liver disease, or kidney disease - You currently smoke or use illicit drugs (or have a history of doing so) - Your blood pressure is 160/100 mmHg or higher - You have obesity (BMI ≥ 35) or high cholesterol - You have had an active infection in the past 2 months - You have a history of seizures, cancer, or inflammatory disease (e.g., gout, rheumatoid arthritis) - Your weight has changed by more than 5% in the past 6 months - You exercise regularly (structured aerobic exercise 3 or more times per week) - You are currently on hormone replacement therapy Talk to your doctor to see if this trial is right for you.