RecruitingNot ApplicableNCT05523505

Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults

Bridging the Gap Between Brain Network Science and High-definition Non-invasive Brain Stimulation to Develop a Scalable Adult Literacy Intervention


Sponsor

Vanderbilt University

Enrollment

100 participants

Start Date

Nov 7, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this project is to address the urgent need for effective, scalable adult literacy interventions by integrating breakthroughs in two separate fields: 1.) the brain network science of resilience to reading disorders and 2.) high-definition non-invasive brain network stimulation. This study will first establish the efficacy of a novel, noninvasive stimulation protocol on reading behavior and brain metrics; then will determine how stimulation-induced effects interact with baseline reading comprehension ability; and lastly, will identify whether stimulation-induced effects are more clinically-beneficial than canonical behavioral interventions. Results may change the foundation for how we treat low adult literacy, and have the potential for wider reaching impacts on non-invasive stimulation protocols for other clinical disorders.


Eligibility

Min Age: 18 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called RLN and CCN real non-invasive brain stimulation intervention, a medical device called RLN real non-invasive brain stimulation intervention, and others for people with reading disability. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 40 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICESham intervention

Use of the non-invasive brain stimulation device to simulate peripheral experience of stimulation without actually stimulating the brain.

DEVICERLN real non-invasive brain stimulation intervention

Real non-invasive brain stimulation to the left angular gyrus using transcranial alternating current stimulation (tACS).

DEVICERLN and CCN real non-invasive brain stimulation intervention

Real non-invasive brain stimulation to the left dorsolateral prefrontal cortex and left angular gyrus using transcranial alternating current stimulation (tACS).


Locations(1)

Vanderbilt University Medical Center

Nashville, Tennessee, United States

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NCT05523505


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