RecruitingNCT05526443

Austrian Registry for Evaluation of Treatment Patterns and Outcome in Patients With Advanced Pancreatic Ductal Adenocarcinoma (PDAC)


Sponsor

Medical University of Graz

Enrollment

1,500 participants

Start Date

Jan 13, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

To systematically collect and analyse real-world data on treatment patterns, clinical outcomes and toxicities among patients with advanced pancreatic ductal adenocarcinoma (PDAC) undergoing systematic treatment in Austria


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • years, female and male
  • ECOG (Eastern Cooperative Oncology Group) Scale 0-2
  • Diagnosis of histologically confirmed locally advanced inoperable and/or metastatic PDAC
  • Patients undergoing palliative 1st line therapy with a platinum- or gemcitabine- based chemotherapy in case of previous (neo)adjuvant therapy also patients who receive nal-Irinotecan/5-FU/Leukovorin as palliative first line are eglible
  • Signed informed consent for prospective patients, for retrospective cases no informed consent is required

Exclusion Criteria2

  • Patients with locally advanced operable PDAC who do not receive palliative chemotherapy
  • Patients with locally advanced borderline resectable PDAC who do not receive palliative chemotherapy

Interventions

DRUGall approved chemotherapeutic agents from second line

all approved chemotherapeutic agents from second line


Locations(12)

Medical University Graz Department of Oncology

Graz, Styria, Austria

Ordensklinikum Linz

Linz, Upper Austria, Austria

Landesklinikum Amstetten

Amstetten, Austria

Landesklinikum Feldkirch

Feldkirch, Austria

Krankenhaus der Barmherzigen Brüder

Graz, Austria

Universitätsklinikum Innsbruck,

Innsbruck, Austria

Landesklinikum Klagenfurt

Klagenfurt, Austria

Universitätsklinikum St. Pölten

Sankt Pölten, Austria

Barmherzige Schwestern Krankenhaus Wien

Vienna, Austria

Pancreatic Cancer Unit des Comprehensive Cancer Center (CCC-PCU)

Vienna, Austria

St. Josef Krankenhaus Wien

Vienna, Austria

Krankenhaus St. Vinzenz Zams

Zams, Austria

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NCT05526443


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