RecruitingNCT05531461
Cognition and Imaging With Tigertriever
COGNITIVE Study- Cognition and Imaging With Tigertriever
Sponsor
Rapid Medical
Enrollment
424 participants
Start Date
Oct 28, 2024
Study Type
OBSERVATIONAL
Conditions
Summary
The objective of the COGNITIVE Study is to evaluate whether successful reperfusion with Tigertriever is associated with cognitive benefit.
Eligibility
Min Age: 18 YearsMax Age: 75 Years
Inclusion Criteria5
- Patients admitted with large vessel occlusion (LVO) and treated with the Tigertriever, as indicated per the approved IFU.
- Tigertriever was used as the first line treatment in the target vessel.
- A signed informed consent.
- Age 18-75 years (inclusive).
- No known significant pre-stroke disability (pre-stroke mRS 0 or 1).
Exclusion Criteria9
- Use of any other IA recanalization device prior to the Tigertriever in the target vessel, including aspiration catheter.
- Evidence of acute brain hemorrhage on CT and/or MRI at admission.
- Prior hemorrhage, stroke, thrombolysis, and/or endovascular therapy in the last 3 months.
- Probable cerebral amyloid angiopathy.
- Pre-stroke diagnosed dementia and/or prescribed cholinesterase inhibitors.
- Pre-stroke diagnosed and/or currently treated major depression.
- Pre-stroke learning or intellectual disability.
- Anticipated inability to obtain 6-month follow-up assessments.
- \-
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Locations(3)
View Full Details on ClinicalTrials.gov
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NCT05531461
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