RecruitingNCT05531461

Cognition and Imaging With Tigertriever

COGNITIVE Study- Cognition and Imaging With Tigertriever


Sponsor

Rapid Medical

Enrollment

424 participants

Start Date

Oct 28, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The objective of the COGNITIVE Study is to evaluate whether successful reperfusion with Tigertriever is associated with cognitive benefit.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria5

  • Patients admitted with large vessel occlusion (LVO) and treated with the Tigertriever, as indicated per the approved IFU.
  • Tigertriever was used as the first line treatment in the target vessel.
  • A signed informed consent.
  • Age 18-75 years (inclusive).
  • No known significant pre-stroke disability (pre-stroke mRS 0 or 1).

Exclusion Criteria9

  • Use of any other IA recanalization device prior to the Tigertriever in the target vessel, including aspiration catheter.
  • Evidence of acute brain hemorrhage on CT and/or MRI at admission.
  • Prior hemorrhage, stroke, thrombolysis, and/or endovascular therapy in the last 3 months.
  • Probable cerebral amyloid angiopathy.
  • Pre-stroke diagnosed dementia and/or prescribed cholinesterase inhibitors.
  • Pre-stroke diagnosed and/or currently treated major depression.
  • Pre-stroke learning or intellectual disability.
  • Anticipated inability to obtain 6-month follow-up assessments.
  • \-

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Locations(3)

University of California

Los Angeles, California, United States

Corewell Health Research Institute

Grand Rapids, Michigan, United States

Westchester Medical Center

New York, New York, United States

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NCT05531461


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