RecruitingNot ApplicableNCT05540704

Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes

Changing the T1DE (Type 1 Diabetes Eating Disorders): A Randomized Controlled Trial Comparing Acceptance and Commitment Therapy (ACT) to Supportive Diabetes Counseling and a Waitlist Control


Sponsor

Duke University

Enrollment

235 participants

Start Date

Apr 4, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to test whether a new intervention works to treat eating disorders in type 1 diabetes. Participants are assigned to one of the following: (1) Acceptance and Commitment Therapy (ACT), (2) Supportive Diabetes Counseling, or (3) a 6-month Waitlist Control. Participants in the ACT and Supportive Diabetes Counseling conditions complete 12 sessions over 12-16 weeks and use their mobile phone between sessions to increase engagement and reinforce learning. The main questions are: Does treatment improve glycemic levels, eating disorder symptoms, diabetes management and diabetes distress? Does one treatment do better than the other? How do the treatments work, if they work, and for whom? Participants complete assessments that include wearing a continuous glucose sensor and activity watch, and get a blood draw to determine HbA1c. They also complete diagnostic interviews, surveys and computer tests of attention and things like heart rate and reaction time. These assessments help us better understand the types of changes that are happening and how they might influence health and well-being.


Eligibility

Min Age: 16 YearsMax Age: 50 Years

Inclusion Criteria10

  • Primary Cohort
  • years of age
  • Diagnosis of Type 1 diabetes
  • Eating disorder characterized by binge eating and/or problematic weight control behaviors, including withholding insulin (Bulimia Nervosa, Binge Eating and Purging Disorder spectrum diagnoses)
  • Independently manages diabetes (not reliant on a caregiver)
  • Expansion Cohort
  • years of age
  • Diagnosis of Type 1 diabetes
  • DEPR-R score \>=20 but does not meet criteria for the primary cohort
  • Primary and Expansion Cohort

Exclusion Criteria5

  • Active suicidal ideation
  • Diagnosis of Avoidant Restrictive Food Intake Disorder or Anorexia Nervosa spectrum diagnoses
  • Hypoglycemic unawareness as assessed by the Gold Method and multiple severe episodes of hypoglycemia requiring 3rd party assistance in the last 2 years
  • Current substance abuse disorder or current or past psychotic disorder
  • NonEnglish speaking

Interventions

BEHAVIORALACT

Treatment is based on Acceptance and Commitment Therapy (ACT), a contemporary cognitive behavioral therapy (CBT) that improves human functioning and adaptability by increasing psychological flexibility. Individual therapy sessions are paired with mobile phone delivered interventions.

BEHAVIORALSupportive Diabetes Counseling

Counseling with a diabetes educator knowledgeable about disordered eating in type 1 diabetes. Intervention focuses on supportive listening, diabetes-related education, including management problems and goal setting.


Locations(2)

Duke University

Durham, North Carolina, United States

Brown University

Providence, Rhode Island, United States

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NCT05540704


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