RecruitingNCT05545176

The Validation and Development of Termination-of-Resuscitation (TOR) Rules in OHCA Patients in Asia Countries

The Validation and Development of Termination-of-Resuscitation (TOR) Rules in Patients Following Out-of-Hospital Cardiac Arrest (OHCA) in Asia Countries


Sponsor

National Taiwan University Hospital

Enrollment

140,000 participants

Start Date

Jan 1, 2007

Study Type

OBSERVATIONAL

Conditions

Summary

Objectives/Hypotheses 1. Prehospital termination-of-resuscitation (TOR) rules were developed in North American and European sites. Whether they remained valid in different geographic, ethnic, and cultural background areas is still under debate. 2. Differences in characteristics of out-of-hospital cardiac arrests (OHCAs) and configurations of emergency medical service (EMS) between the Western and Asian countries, including relatively lower rate of presenting shockable rhythm (i.e. ventricular fibrillation / ventricular tachycardia; VF/VT), lower rates of bystander CPR, less advanced life support (ALS) implementation, and less public access defibrillators, might create potential threats to the prediction accuracy of TOR rules. 3. We aim to conduct a study to validate the performance of ever published TOR rules in Asian OHCA population, including non-traumatic, traumatic, and pediatric OHCA patients. Furthermore, assess the possible variables that may impact the performance of TOR rules. 4. We also aim to develop new TOR rules based on PAROS registry for Asia population, focusing on non-traumatic, traumatic, and pediatric OHCA patients, respectively.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This observational study aims to validate and potentially improve the accuracy of "termination of resuscitation" (TOR) rules — guidelines used by emergency responders to decide when to stop CPR for out-of-hospital cardiac arrest (OHCA) — in Asian populations, where patient characteristics and emergency systems differ from Western countries where these rules were developed. Researchers will use data from the PAROS (Pan-Asian Resuscitation Outcomes Study) registry to assess existing TOR rules and develop new, Asia-specific ones for adults, trauma patients, and pediatric patients. Eligible subjects are adult OHCA patients transported by emergency medical services, excluding those with obvious signs of death, do-not-resuscitate orders, or missing key data. This is an observational study using existing registry data, so individual participants are not enrolled or treated differently from standard emergency care. This summary was prepared using AI to help patients understand the study in plain language.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERtermination of resuscitation rules

Use retrospective data to analyze the accuracy termination of resuscitation rules and further develope a termination of resuscitation rule.


Locations(1)

National Taiwan University

Taipei, Taiwan

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NCT05545176


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