RecruitingNot ApplicableNCT05547035

Identification of Physiological Data by a Wearable Monitor in Subjects Suffering From Major Depression Disorders

Prospective, Multicenter Non-randomised, Open-label Study Evaluating the Correlation Between Physiological Data Measured by a Portable Sensor and Psychometric Assessment


Sponsor

Digital For Mental Health

Enrollment

200 participants

Start Date

Sep 5, 2017

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate, over a period of six months, the links between physiological data collected such as electrodermal activity (or Galvanic Skin Response), motor activity measured by accelerometer, heartbeat measured by photoplestimograph and the clinical evaluation performed by the physician, in patients suffering from major depression disorder.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria1

  • Patient able to give written informed consent, - Presenting a major depressive episode defined according to DSM V criteria, - Presenting a MADRS score ≥ 20 - Able to understand all study procedures and follow-up

Exclusion Criteria12

  • \- Inability to wear the wearable monitor for the duration of the study (6 months)
  • Patient with a severe medical condition at the discretion of the investigator (neurological, rheumatological, etc.)
  • Resistant depression
  • Chronic depression, dysthymia
  • Depression with psychotic features not congruent with mood, schizophrenia disorder
  • Depression with catatonic features
  • Substance use disorder in the last 6 months
  • Extreme sports during the conduct of the study
  • Pre-existing skin infection at the wearable monitor site
  • Pregnant or lactating woman
  • Participation in another drug or medical device study
  • Inability to give informed consent

Interventions

BEHAVIORALPatient follow-up of depression

All patients who agree to participate in the study are diagnosed by their GP/Psychiatrist with a diagnostic assessment instrument called DSM-5. Participants visit their GPs/Psychiatrists at baseline, month 1, month 2, month 3, month 4, month 5 and month 6. At each visit, the GPs/Psychiatrists: * assess the depression severity by using MADRS scale * assess the severity of illness at time of assessment compared with start of treatment by using CGI-S measures * the patient complete the self-administered questionnaire of HAD scale that measures the symptoms of anxiety and depression.


Locations(11)

135 rue Nestor Longue Epee

Bersée, France

203 rue de la Motte

Bersée, France

APPT 22 Residence les Tilleuls

Dax, France

2 boulevard Winston Churchill

Dijon, France

2 boulevard Winston Churchill

Dijon, France

Clinique Lyon Lumiere

Meyzieu, France

22 rue Jacques Boutrolles

Mont-Saint-Aignan, France

19 rue de la Liberté

Nice, France

119 rue de la Pompe

Paris, France

91 rue Caulaincpurt

Paris, France

145 avenue des Minimes

Toulouse, France

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NCT05547035


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