RecruitingPhase 3NCT05551104

Safest Choice of Antihypertensive Regimen for Postpartum Hypertension

Safest Choice of Antihypertensive Regimen for Postpartum Hypertension: A Randomized Control Trial (SCARPH)


Sponsor

Loma Linda University

Enrollment

500 participants

Start Date

May 8, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this investigator-initiated randomized control trial is to determine whether oral Nifedipine versus oral Labetalol is superior in controlling high blood pressures in the postpartum period.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is comparing two blood pressure medications — nifedipine and labetalol — to find out which is safer and more effective for women who develop high blood pressure after giving birth (postpartum hypertension). **You may be eligible if...** - You are a woman who develops high blood pressure after delivery - Your blood pressure is at a level that requires medication (systolic 140+ or diastolic 90+ on two readings, or a single very high reading) - You have just given birth and are in the postpartum period **You may NOT be eligible if...** - You have moderate-to-severe asthma, coronary artery disease, heart failure, or certain heart rhythm problems - You have a contraindication to either nifedipine or labetalol - Your heart rate is below 60 or above 110 - Your primary language is not the language used in the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGOral Nifedipine

Administration of oral nifedipine to control postpartum hypertension.

DRUGOral Labetalol

Administration of oral labetalol to control postpartum hypertension.


Locations(1)

Loma Linda University Health

Loma Linda, California, United States

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NCT05551104


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