The Efficacy and Safety of Silodosin Singly or Combined With Ningmitai Capsules in the Treatment of Benign Prostatic Hyperplasia

This study is comparing two treatments for benign prostatic hyperplasia (BPH) — an enlarged prostate that makes it difficult to urinate. The two treatments being tested are silodosin (a medication that relaxes the prostate) used alone, versus silodosin combined with Ningmitai capsules (a traditional Chinese medicine). Researchers want to see which approach is more effective and safer for older men with bothersome urinary symptoms. You may be eligible if: - You are male and between 60 and 80 years old - You have been diagnosed with BPH - Your symptom score (IPSS) is 8 or higher - Your urine flow rate (Qmax) is between 4 and 15 mL/s with adequate urine volume - Your prostate volume is 30 mL or larger by ultrasound You may NOT be eligible if: - You have prostate cancer or any other cancer - Your PSA levels indicate a possible cancer risk - You have bladder, urethral, or nerve-related causes of your urinary symptoms - You have had prostate surgery, microwave therapy, or other invasive procedures - You have taken alpha blockers or certain other prostate medications recently - You have serious heart, liver, kidney, blood, or respiratory disease - You have poorly controlled diabetes (fasting blood glucose ≥ 10 mmol/L) Talk to your doctor to see if this trial is right for you.