RecruitingNot ApplicableNCT05553899

Utility of PET-MRI in Surveillance of Paediatric Brain Tumours

Utility of PET-MRI in Post-treatment Surveillance of Paediatric Brain Tumours: a Pilot Study

Sponsor

Sheffield Children's NHS Foundation Trust

Enrollment

5 participants

Start Date

Feb 28, 2024

Study Type

INTERVENTIONAL

Conditions

Brain Tumor, Pediatric

Summary

This is a pilot project to explore the utility of PET-MRI in the post-treatment surveillance of high-grade gliomas or medulloblastomas in children in our institution.

Eligibility

Min Age: 8 YearsMax Age: 18 Years

Inclusion Criteria4

Have a presumptive or histologically confirmed diagnosis of a malignant brain tumour requiring treatment
Diagnostic uncertainty about tumour recurrence post-treatment based on conventional MR imaging in the opinion of the MDT
Have a life expectancy of at least three months
Able to comply with an MRI scan without a general anaesthetic

Exclusion Criteria5

Unable to comply with an MRI scan without a general anaesthetic
Diabetes or other causes of hyperglycaemia
Pregnancy
Patient body habitus above scanner dimensions
Standard contra-indication to MRI (eg. pacemaker, non-compatible metallic implants, altered renal function)