RecruitingNCT05556642

Relapsed and Refractory Hepatoblastoma: A Prospective Registry and Liver Tumor Research Consortium Initiative

Relapsed and Refractory Hepatoblastoma: A Prospective Registry and Hepatic Tumors Research Consortium Initiative


Sponsor

Children's Hospital Medical Center, Cincinnati

Enrollment

500 participants

Start Date

Sep 7, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

There are limited data regarding the biology and treatment of relapsed/refractory hepatoblastoma (rrHBL). This project provides the infrastructure for acquisition of biological specimens, imaging, and correlative clinical data to facilitate biology studies and characterization of rrHBL. This registry will collect clinical, demographic, and pathological data, specimens (as available) and imaging from patients with rrHBL, prospectively. Cases are identified through: 1. Existing clinical and/or cancer registry databases 2. Referrals from clinicians, surgeons, or pathologists 3. Families initiating contact with Registry staff directly


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is creating a registry of children and young patients with relapsed or hard-to-treat hepatoblastoma (a rare type of liver cancer in children) to better understand the disease and help develop new treatment options. It also collects tumor tissue to build models for future research. **You may be eligible if:** - You have a suspected or confirmed diagnosis of relapsed or refractory hepatoblastoma - You were under 6 years old when first diagnosed (for a related liver cancer type) - You, a parent, or legal guardian can provide written consent **You may NOT be eligible if:** - There are no formal exclusion criteria for this registry study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBiospecimen collection

Clinical information and biospecimens will be collected


Locations(1)

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States

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NCT05556642


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