Safety and Efficacy Evaluation of BZ371A Topically Applied on Prostatectomized Patients

This study is testing a topical cream called BZ371A applied to the penis of men who have had their prostate removed (prostatectomy) for cancer, to see if it helps preserve or restore the ability to get erections after surgery. **You may be eligible if:** - You are a man between 40 and 65 years old - You identify as heterosexual - You had your prostate removed for cancer without spreading to other organs, within the last 60 days - You had normal erectile function before surgery (IIEF questionnaire score above 22) - You have a stable sexual partner and are continuing that relationship - You are already using a daily low-dose tadalafil (a common erectile dysfunction drug) as part of your recovery **You may NOT be eligible if:** - Your prostate cancer was advanced (T3 or T4 stage) - You had open or perineal (non-robotic/non-laparoscopic) prostatectomy - You need additional cancer treatment (radiation or hormone therapy) - You have uncontrolled diabetes - You have low testosterone or are using male hormone therapy - You currently have depression or are on antidepressants Talk to your doctor to see if this trial is right for you.