RecruitingNot ApplicableNCT05566483
Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity
Physiological Underpinnings of Post-Acute Sequelae of SARS CoV-2 ("Long COVID") and Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity
Sponsor
University of Colorado, Denver
Enrollment
30 participants
Start Date
Mar 1, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
The primary objectives of this study are to determine whether exercise training is an effective strategy for treatment of Long COVID and characterize the cardiorespiratory and autonomic physiology in these patients to precisely characterize mechanisms contributing to this syndrome.
Eligibility
Min Age: 18 Years
Inclusion Criteria1
- Adults ≥18 years with documented history of COVID-19 infection and symptoms consistent with Long COVID lasting >12 weeks after diagnosis.
Exclusion Criteria5
- History of cardiovascular/pulmonary disease prior to infection
- COVID-related myocardial injury such as evidence of myocarditis
- Deep vein thrombosis/pulmonary embolism following COVID-19 infection
- Exercise intolerance resulting from conditions that are not related to cardiorespiratory or autonomic factors (e.g. osteoarthritis or other musculoskeletal diseases);
- Dependency of supplemental oxygen following COVID infection due to cardiovascular and/or pulmonary complications following acute COVID infection
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Interventions
BEHAVIORALExercise
exercise protocol
Locations(1)
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NCT05566483