RecruitingPhase 2NCT05574127

A Study of Brief Behavioral Activation for the Treatment of Depression in Older Adult Cancer Survivors

Brief Behavioral Activation for the Treatment of Depression in Older Adult Cancer Survivors

Sponsor

Memorial Sloan Kettering Cancer Center

Enrollment

90 participants

Start Date

Oct 6, 2022

Study Type

INTERVENTIONAL

Conditions

Survivorship

Summary

The purpose of this study is to find out if a psychotherapy method called behavioral activation (BA) can be successfully delivered by telephone or videoconference (remotely) and can effectively treat depression in Older Adult Cancer Survivors (OACS)

Eligibility

Min Age: 65 Years

Inclusion Criteria10

As per self-report or medical record, ≥65 years old
As per self-report or medical record, has a history of cancer
As per medical record and/or clinician confirmation:
a patient in MSK Survivorship Clinics AND/OR
no evidence of disease (NED) AND/OR
months or more post-treatment (patients on maintenance hormonal therapies are eligible)
Fluent in English, as per self-reported fluency of "well" or "very well"*
As per self-report, able to communicate over video-conference and/or phone for sessions
Elevated score on the PHQ-9: ≥5 (N/A for Training Case participants)
Received a Blessed Orientation-Memory-Concentration Scale (BOMC) score of ≤ 11 (N/A for Training Case participants)

Exclusion Criteria4

As per PI determination, requires a higher level of care for current passive or active suicidal ideation than current protocol is able to provide. If a participant receives a score of > 0 on item 9 of the PHQ-9, they will be referred to study PI for further evaluation. They will be excluded from participation in this study if the PI determines they would be appropriate for a higher level of care than BA may be able to provide.
As per self-report or as documented in the medical record, current untreated (e.g., no medication, no therapy) major psychotic disorder (schizotypal personality disorder, schizophreniform disorder, schizoaffective disorder). Patients diagnosed with a major psychiatric disorder will be reviewed by the study PI to determine eligibility prior to consent.
As per self-report or medical record, currently taking antidepressant medication for < 3 month
As per medical record, patient has impaired decision-making capacity

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Interventions

BEHAVIORALBehavioral Activation

Sessions for both arms (BP \& SP) will be administered remotely via video-conference and/or telephone (per patient preference) at the following timeline: * Full participants (not training cases): Ten sessions (30-50 minutes each) will be delivered approximately weekly over a 10-week period (+10 weeks). * Training case participants: Ten sessions (30-50 minutes each) will be delivered over an approximately 5-week period (+10 weeks).

BEHAVIORALSupportive Psychotherapy