RecruitingNCT05575440

Evaluation of 18F-TFB PET/CT Scan in Patients With Differentiated Thyroid Cancer

Evaluation of F-18 Tetrafluoroborate (18F-TFB) PET/CT in Patients With Differentiated Thyroid Cancer


Sponsor

Mayo Clinic

Enrollment

24 participants

Start Date

Apr 22, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This phase II study evaluates F-18 tetrafluoroborate (18F-TFB) PET/CT scan in patients with differentiated thyroid cancer. Diagnostic imaging is necessary for planning treatment, monitoring therapy response, and identifying sites of recurrent or metastatic disease in differentiated thyroid cancer. 18F-TFB PET/CT may accurately detect recurrent and metastatic thyroid cancer lesions, with the potential to provide information for patient management that is better than the current standard of care imaging practices.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing a newer PET/CT scan using a tracer called 18F-TFB against the standard imaging test (iodine scan) for detecting thyroid cancer. The goal is to see whether the newer scan provides better or more accurate information. **You may be eligible if...** - You are 18 or older - You have confirmed papillary or follicular thyroid cancer (diagnosed by biopsy) - Your doctor has already recommended a standard iodine (TBI) scan - You are willing to also undergo the 18F-TFB PET/CT scan - You are not pregnant and can lie still for about 65 minutes in a scanner **You may NOT be eligible if...** - You had a contrast CT scan in the past 4 weeks - You have taken amiodarone (a heart drug) in the past 4 months - You have recently taken iodine supplements or iodine-containing products - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREComputed Tomography

Undergo a PET/CT scan

RADIATIONFluorine F 18 Tetrafluoroborate

Given IV

PROCEDUREPositron Emission Tomography

Undergo a PET/CT scan

OTHERSurvey Administration

Ancillary studies


Locations(1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

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NCT05575440


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