Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients
Longitudinal Prospective Study of Neurocognitive Outcomes and Multimodal Quantitative Neuroimaging Outcomes in Primary Brain Tumor Patients Receiving Brain Radiotherapy
Jona Hattangadi-Gluth
250 participants
Jan 1, 2015
OBSERVATIONAL
Conditions
Summary
In this proposal, the investigators introduce a novel, translational study to prospectively examine primary brain tumor patients undergoing fractionated radiation therapy to the brain. Quantitative neuroimaging, radiation dose information, and directed neurocognitive testing will be acquired through this study to improve understanding of cognitive changes associated with radiation dosage to non-targeted tissue, and will provide the basis for evidence-based cognitive- sparing brain radiotherapy.
Eligibility
Inclusion Criteria5
- Patients 18 years or older
- Karnofsky performance status (KPS) ≥70
- Life expectancy of ≥1 year
- Primary brain tumor patients who will receive fractionated partial brain RT
- Able to complete neurocognitive assessments
Exclusion Criteria2
- Inability to undergo MRI with contrast
- Prior brain RT
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05576103