RecruitingNCT05577689

Novel Therapy Target in Metastatic Prostate Cancer

Combining Multi-omics Analysis and Organoid Models to Search for Novel Therapy Target in Metastatic Prostate Cancer


Sponsor

Fudan University

Enrollment

100 participants

Start Date

Aug 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this study is to use multiomics sequencing to explore the molecular characteristics of metastatic prostate cancer (mPCa), especially metastatic castration-resistant prostate cancer (mCRPC). At the same time, mCRPC models will be constructed, including organoids and animal models, serving as a basic and translational research platform to help identify novel drug targets for mPCa.


Eligibility

Sex: MALEMin Age: 18 Years

Inclusion Criteria4

  • Histologically confirmed prostate cancer
  • metastatic disease confirmed by image examination
  • Patients who can undergo surgery or biopsy for prostate cancer
  • Able to provide informed consent

Exclusion Criteria4

  • Patients diagnosed with other types of cancer besides prostate cancer
  • Not accessible to surgery sample
  • Patients fail to provide informed consent
  • Other situation that researchers think are unsuitable for this study

Interventions

OTHERTissue

Tissue will be derived from patients during a standard of care procedure


Locations(1)

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China

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NCT05577689


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