A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis

This study is testing whether bright light therapy — sitting in front of a special bright light box each day — can help people with Crohn's disease or ulcerative colitis by improving gut barrier function and reducing inflammation. It's a crossover trial, meaning participants try both the light therapy and a comparison condition. **You may be eligible if...** - You are 18 or older - You have been diagnosed with Crohn's disease or ulcerative colitis confirmed by biopsy - Your inflammation markers are mildly elevated, or you have fatigue - You have been on a stable dose of your IBD medication (biologic, immunomodulator, or anti-inflammatory) for at least 12 weeks **You may NOT be eligible if...** - Your IBD is currently in a significant flare - You have been diagnosed with major depression or have thoughts of self-harm - You have sleep apnea or restless leg syndrome (based on screening questionnaires) - You regularly take medications that affect gut permeability or melatonin levels (like NSAIDs, beta blockers, or metoclopramide) Talk to your doctor to see if this trial is right for you.